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Table 2 Power for detecting significant correlations between interacting loci

From: Methods for detecting gene × gene interaction in multiplex extended pedigrees

  

Population

Phenotype

Disease loci

AIa

KAa

DAa

NYb

KPD

D1 and D2

0.11

0.05

0.28

0.09

 

D1 and D4

0.06

0.2

0.04

0.13

 

D2 and D3

0.1

0.14

0.1

0.07

 

D3 and D4

0.07

0.02

0.07

0.07

P1

D1 and D2

0.12

-

0.28

0.07

P2

D2 and D3

0.17

0.14

-

0.1

 

D3 and D4

0.01

0.02

-

0.01

P3

D1 and D4

0.26

0.24

-

0.16

 

D2 and D3

0.12

0.11

-

0.06

  1. a multipoint estimates
  2. b single-point estimates
  3. Power is based on the proportion of times a positive correlation between two loci had a one-sided p-value < 0.05. Based on 100 replicates.