Skip to main content

Table 1 Most significant peaks for LODPAL, OSA, and pre-cluster

From: Analysis of alcohol dependence phenotype in the COGA families using covariates to detect linkage

Chr Position (cM) Locus Covariate Linked cluster/subset and sizea LOD score -log10 (p-value)
LODPAL
3 160.00 ATA34G06   NA 4.72 >4.48
4 61.00 GABRB1 ecb21 NA 6.61 >4.48
12 187.00 D12S1045 ttth1 NA 4.26 >4.48
OSA
4 p-ter D4S2366 ttth1 H2L [42 out of 156 ] 2.48 2.44
7 62.19 D7S2846 Age of onset H2L [35 out of 156] 3.09 3.30
10 148.19 D10S544 ttth1 H2L [41 out of 156] 3.40 3.32
Pre-cluster
10 194.37 D10S590 ecb21 G2 [101 out of 142] 2.10 2.89
11 90.91 D11S2002 ttth1 G1 [36 out of 133] 1.90 2.68
21 73.68 D21S1446 ecb21 G2 [108 out of 149] 1.86 2.62
GENEHUNTER-PLUS
10 148.19 D10S544 NA NA 2.86 >4.48
  1. aThe numbers within square brackets in the "Linked cluster/subset" column represent the cluster or subset size in terms of ASPs for pre-cluster and pedigrees for OSA.