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Table 1 Regions detected for heterogeneity with either the PST or the TTS (p ≤ 0.005) in the two sets of data

From: Impact of the diagnosis definition on linkage detection

   

First set

Second set

Regions

Trait

Population

TTS

PST

TTS

PST

Chr 1 markers 23–25

a

AI

0

17.8c (181.2 cM)a

0.3

10.8d (173.6 cM)

  

KA

0.02

10.3d (173.6 cM)

0.3

10.8d (173.6 cM)

  

DA

0

11.3d (189.5 cM)

0.1

16.3c (173.6 cM)

 

bb

AI

0.1

19.1c (173.6 cM)

0.05

11.8d (173.6 cM)

  

KA

0.9

6.2f (173.6 cM)

0.34

9.2e (173.6 cM)

Chr 3 marker 42

bb

KA

0.1

11.5d (287 cM)

0

14.3d (287 cM)

  

AI

0

4.5 (287 cM)

0

10e (287 cM)

Chr 9 markers 1–4

k

AI

0.8

11.1d (0.075 cM)

0.2

11.8d (0.075 cM)

  

KA

0.1

18.5c (0 cM)

0.3

4.7 (0.23 cM)

 

l

AI

0

9.4e (0.075 cM)

0

7.9e (0.135 cM)

  

KA

0

19.1c (0 cM)

0

6.6f (0.075 cM)

  1. a distance between the first marker of the chromosome and the peak score
  2. b the trait b was present in all affected subjects in population DA and could not be tested here for heterogeneity.
  3. c p ≤ 0.0001
  4. d p ≤ 0.001
  5. e p ≤ 0.005
  6. f p ≤ 0.05