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Table 1 Genotypic TDT results among the 73 trios and the 39 high susceptibility scoring trios

From: Use of susceptibility scoring in conjunction with the genotypic transmission disequilibrium test

 

No. of information families

Beta, p-value

SNP (heterozygosity)

among 73 trios

among 39 high risk trios

73 trios

39 trios whose susceptibility residuals are above 0.30

Chromosome 4

    

   rs207338 (0.50)

57

29

0.29514, 0.1966

0.11173, 0.7092

   rs1965907 (0.50)

54a

29

-0.58566, 0.0157

-0.64366, 0.0472

   rs1040288 (0.50)

51

27

-0.36050, 0.1447

-0.23231, 0.4968

   rs1478224 (0.48)

55

28

-0.70536, 0.0044

-0.54712, 0.1042

   rs1472370 (0.50)

57

29

-0.37529, 0.1142

-0.58778, 0.0783

   rs2178299 (0.44)

49

24

-0.36756, 0.1674

-0.59887, 0.1288

Chromosome 15

    

   rs965471 (0.47)

51b

28

-0.55324, 0.0318

-0.82098, 0.0233

   rs1648308 (0.50)

53

28

0.74246, 0.0049

1.09121, 0.0045

   rs1648312 (0.50)

53

28

-0.82091, 0.0019

-1.17132, 0.0023

   rs2014638 (0.50)

62

33

0.22641, 0.3153

0, 1.0

   rs1858359 (0.49)

57

27

0.29755, 0.2152

0.39855, 0.2627

   rs725463 (0.50)

48

24

0.50450, 0.0665

0.83387, 0.0485

   rs749468 (0.50)

52

29

0.28379, 0.2770

0.24181, 0.4905

   rs872263 (0.20)

32

14

0.27193, 0.4125

-0.11765, 0.8087

   rs2046071 (0.50)

56

30

0.51080, 0.0421

0.30718, 0.3628

   rs1021393 (0.50)

58

29

0.06780, 0.7713

-0.05634, 0.8667

Chromosome 16

    

   rs8466 (0.31)

37

15

0.17588, 0.5816

0.54753, 0.3151

   rs1019141 (0.50)

55

31

0.14948, 0.5223

0.20196, 0.5019

   rs904821 (0.49)

50

23

0.38778, 0.1409

0.25025, 0.5113

   rs991911 (0.48)

57

32

-0.33455, 0.1675

-0.33946, 0.2794

   rs41383 (0.50)

52

28

-0.78702, 0.002

-0.55849, 0.1021

   rs1541979 (0.47)

47

27

-0.34302, 0.1836

-0.25783, 0.4246

   rs1074963 (0.47)

52

28

0.27269, 0.2585

0.31063, 0.3595

   rs1037973 (0.47)

46

25

-0.31845, 0.2352

-0.43531, 0.2606

   rs873857 (0.48)

47

24

0.11185, 0.6588

-0.35322, 0.3275

  1. aRed text indicates susceptibility scoring results in larger p-values.
  2. bBlue text indicates susceptibility scoring results in smaller p-values.