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Table 1 p-Values for the two tests of G×A interaction (gsdalc = gsdnalc and ρG = 1) for several quantitative phenotypes.

From: Effect of genotype × alcoholism interaction on linkage analysis of an alcoholism-related quantitative phenotype

  

p-Values

  

COGA

DSM-IV

Trait

G×A interactiona

Aldx1a

Aldx1b

Aldx2a

Aldx2b

lnMXDRNK

gsdalc = gsdnalc

0.359

0.001

0.242

0.018

 

ρG = 1

0.118

0.006

0.006

0.071

cigpky

gsdalc = gsdnalc

0.452

0.639

0.728

0.329

 

ρG = 1

0.067

0.075

0.004

0.038

ecb211

gsdalc = gsdnalc

0.145

0.730

0.246

0.397

 

ρG = 1

1.000

1.000

0.450

0.496

ttth1

gsdalc = gsdnalc

0.729

0.804

0.772

0.853

 

ρG = 1

0.352

1.000

0.211

1.000

ttth3

gsdalc = gsdnalc

0.453

0.510

0.425

0.971

 

ρG = 1

0.362

0.348

0.227

0.227

ttdt3

gsdalc = gsdnalc

0.829

0.793

0.814

0.695

 

ρG = 1

0.135

0.493

0.200

0.081

ntth4

gsdalc = gsdnalc

0.172

0.702

0.236

0.716

 

ρG = 1

1.000

1.000

1.000

1.000

  1. a gsdalc = gsdnalc = difference in magnitude; ρG (correlation in genetic effects) = 1