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Table 1 Comparisons of SNPs and microsatellites for main effect and two-way interaction effect screening. Both microsatellite and SNP analyses show a strong and frequent main effect in chromosome 4, whereas epistatic effects are located differently.

From: A Bayesian genome screening of maximum number of drinks as an alcoholism phenotype with the new Haseman-Elston method

Ranking Chromosome Marginal posterior probabilities
Microsatellites
1 Chr 4 0.21133
2 Chr 6, Chr 13, Chr 16 0.15433
3 Chr 4 (2 markersa), Chr 10 0.13922
4 Chr 23, Chr 17, Chr 7 0.09066
5 Chr 23, Chr 2 0.08533
6 Chr 1 0.08466
7 Chr 13 0.07577
8 Chr 16 0.07422
9 Chr 14 (2 markers) 0.07266
10 Chr 7 0.06944
11 Chr 17 0.06922
12 Chr 3 0.06622
13 Chr 20 0.05766
14 Chr 8 × Chr 15b 0.05644
15 Chr 10 × Chr 17b 0.03244
SNPs
1 Chr 4 0.2068
2 Chr 4 (2 markersa) 0.1793
3 Chr 23 0.1786
4 Chr 4 0.1725
5 Gender 0.1703
6 Chr 3, Chr 13 0.1563
7 Chr 23 0.1516
8 Chr 23 × sexb 0.1461
9 Chr 23 0.1295
10 Chr 4, Chr 6 0.128
11 Chr 6, Chr 23 0.1256
12 Chr 3 0.1247
13 Chr 16 0.1237
14 Chr 7, Chr 4 0.1208
15 Chr 14 0.0209
  1. aTwo markers are ranked.
  2. b Epistatic effect between the two chromosomes
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BMC Genomic Data

ISSN: 2730-6844

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