Table 1 Summary of the type I error for the observed and adjusted LOD score
From: Smoothing of the bivariate LOD score for non-normal quantitative traits
| Â | 2 degrees of freedom | 1 degree of freedom | ||||
|---|---|---|---|---|---|---|
Nominal α | LOD | observed | adjusted | LOD | observed | adjusted |
0.1000 | 0.8088 | 0.1387 | 0.0914 | 0.3566 | 0.1387 | 0.0965 |
0.0500 | 1.1359 | 0.0744 | 0.0413 | 0.5875 | 0.0744 | 0.0429 |
0.0250 | 1.4613 | 0.0403 | 0.0184 | 0.8341 | 0.0403 | 0.0188 |
0.0100 | 1.8883 | 0.0174 | 0.0061 | 1.1752 | 0.0174 | 0.0060 |
0.0010 | 2.9481 | 0.0019 | 0.0003 | 2.0737 | 0.0019 | 0.0002 |
0.0001 | 3.9950 | 0.0002 | 0.0000 | 3.0034 | 0.0002 | 0.0000 |