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Figure 1 | BMC Genetics

Figure 1

From: Comparisons of case-selection approaches based on allele sharing and/or disease severity index: application to the GAW14 simulated data

Figure 1

Results of chi-square test to detect differences in allele frequency between cases and controls using six case-selection strategies. The six case-selection strategies are: i) a randomly selected case (AR); ii) a case showing most IBD sharing with other affected sibs (AB); iii) a case with the most severe disease (AMS); iv) a randomly selected case per linked family (LR); v) a case with most IBD sharing with other affected sibs from linked families only (LB); vi) a case with the most-severe disease chosen from linked families only (LMS). The horizontal dashed lines on both figures denote p-values of 0.05, 0.01, and 0.001, respectively. The regions between the vertical dashed lines represent the haplotype region containing the disease locus.

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BMC Genomic Data

ISSN: 2730-6844

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