Table 3 Age at diagnosis in retinoblastoma patients according to phenotype and type of mutation. Statistical analysis using the Welch's unpaired t test.
| Phenotype | Frameshift | Nonsense | Missense | Splicing | SP vs. NS-MS-FS |
|---|---|---|---|---|---|
| Unilateral | 21.1 | 26.0 | 23.7 | 26.7 | P = 0.7237 |
| Bilateral | 9.5 | 11.8 | 9.4 | 19.3 | P = 0.0025 |
| All | 12.4 | 15.6 | 16.0 | 21.8 | P = 0.0044 |
| Unilateral vs. Bilateral | P = 0.0073 | P = 0.0147 | P = 0.3321 |