Epigenetic predisposition to expression of TIMP1 from the human inactive X chromosome

BMC Genomic Data

Table 2 Stability of methylation and expression of TIMP1 in subclones of four 5-azacytidine induced HPRT reactivants

Subclones	t11-az-4 (-/M)	t11-az-8 (+/M)^a	t11-az-9 (+/M)^a	t11-az-10 (+/M)
TIMP-, methylated (-/M)	10	10	15	3
TIMP+, Methylated (+/M)	0	2^a	2^a	13
TIMP+, Unmethylated (+/U)	0	0	0	1

^aExpression in these branches was initially weak and became silent after time in culture. ELK1 expression was initially retained in one of the t11-az-9 TIMP1+ clones but was not analyzed after TIMP1 expression was lost. The expression of ZNF41/157 was not examined in these subclones.

ISSN: 2730-6844