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Table 1 Retesting the effects of Egfr SNP's on wing shape and size

From: Tests for the replication of an association between Egfr and natural variation in Drosophila melanogaster wing morphology

    

Separately derived a

Jointly derived a

SNP

Termb

Trait

Typec

INB

RR

BC

KI

INB

RR

BC

KI

C31656T

Gtyp × Sex

Area

N

****

.

.

.

****

.

.

.

C30200Td

Gtyp

C1

N

****

**

****

***

****

**

****

***

T31634C

Gtyp × Sex × Pop

C2

N

****

.

.

.

****

.

.

.

T39389C

Gtyp

D1

S

****

.

.

.

****

.

.

.

T40722C

Gtyp × Pop

Area

S

****

.

.

na

****

.

.

na

C30505A

Gtyp

W7

N

***

***

*

**

***

***

**

*

  1. a. As described in the Materials and Methods, PC's were calculated for the datasets individually (separately) or for all the data concatenated (jointly).
  2. b. Term denotes the genetic term most significant in the original study. The same term is reported for the repeats, except for the RR where we could only test genotype effects and sites T31634C and T40722C where the genotype terms are reported as population terms are not available.
  3. c. Type indicates the nature of the polymorphism, N: non-coding and S: synonymous.
  4. d. The significance of the T30200C to C1 association is here reported for the data from Palsson and Gibson 2004. After re-genotyping the p-values reduce to 0.062 and 0.061 for the separately and jointly derived data respectively, when analyzed over the NC and CA populations. Note however that the results for RR and BC are for the re-genotyped data. Significance of terms: "." non-significant, "*": 0.05 > p > 0.01, "**":p > 0.001, "***":p > 0.0001, "****":p > 0.00001. P-values are not adjusted to correct for the seventeen new independent tests conducted.