Skip to main content
Figure 6 | BMC Genetics

Figure 6

From: The missense mutation in Abcg5 gene in spontaneously hypertensive rats (SHR) segregates with phytosterolemia but not hypertension

Figure 6

Biliary cholesterol and sitosterol concentrations. Female F2 rats, on a defined sitosterol diet (see text) had their bile ducts cannulated and bile collected under gravity and analyzed for cholesterol (panel A) or sitosterol (panel B). No differences in the cholesterol content of bile were noted between any of the genotypes. Note that the concentration of cholesterol is approximately 50-fold more than sitosterol. Interestingly, the sitosterol concentration in the F2 HMZ rats was increased significantly by ~ 50% relative to WT and HET rats (panel B).

Back to article page