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Table 4 Frequency distribution for the 120 bp duplicated alleles of the DRD4 promoter

From: The polymorphic nature of the human dopamine D4 receptor gene: A comparative analysis of known variants and a novel 27 bp deletion in the promoter region

Origin of population

Allele frequency (%)

Genotype frequency (%)

  

2N

1

2

N

1/1

1/2

2/2

Caucasian

Hungarian (Szantai et al., 2005)

1196

17.1

82.9

598

3.0

28.3

68.7

 

European-mixed (Seaman et al., 1999)

174

19.5

80.5

    
 

European-mixed (Barr et al., 2001)

308

19.9

80.1

    
 

mean

 

17.9

82.1

 

3.2*

29.4*

67.4*

 

Standard deviation

 

1.5

1.5

    

Asian

Chinese (Xing et al., 2003)

412

37.4

62.6

206

13.6

47.6

38.8

 

Chinese (Seaman et al., 1999)

122

36.1

63.9

    
 

mean

 

37.1

62.9

 

13.8*

46.6*

39.6*

 

Standard deviation

 

0.5

0.5

    

African

African (Seaman et al., 1999)

136

59.6

40.4

 

35.5*

48.2*

16.3*

American

Mayan (Seaman et al., 1999)

106

48.1

51.9

 

23.1*

49.9*

26.9*

  1. * Expected genotype frequencies were calculated from measured allele frequencies assuming Hardy-Weinberg equilibrium in the populations.
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BMC Genomic Data

ISSN: 2730-6844

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