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Table 1 Conditional probabilities* of observed genotypes, given the true genotype of pool j. For k = 2 individuals with SNP locus AB in pool j.

From: Estimating haplotype frequencies in pooled DNA samples when there is genotyping error

 

Observed Unordered Genotypes/Number of A Alleles in Pool j | True Unordered Genotype AABB

α

BBBB/ 0

ABBB/ 1

AABB/ 2

AAAB/ 3

AAAA/ 4

1

0.063

0.250

0.375

0.250

0.063

5

0.0002

0.131

0.737

0.131

0.0002

25

0.000

0.006

0.988

0.006

0.000

125

0.000

0.000

1.000

0.000

0.000

  1. * conditional probabilities computed from the binomial distribution