Figure 1From: The Prader-Willi syndrome murine imprinting center is not involved in the spatio-temporal transcriptional regulation of the Necdin geneImprinted cluster on mouse chromosome 7C. Upper and lower boxes represent genes expressed from the paternal and maternal alleles respectively. Small nucleolar RNAs (snoRNAs) MBII-13, MBII-85 and MBII-52 genes lie within introns of long primary transcripts initiated at the U exons (U9 to U1 exons). Arrows indicate the transcriptional orientation of the genes. Frat3, Mkrn3, Magel2 and Ndn lie within 120 kb and around 1.5 to 2 Mb from the Snurf-Snrpn gene. Location of BAC109 used for the transgenic study is represented.Back to article page