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Table 5 Effect of uncertainty in the prevalence, w: the population value is w = 0.045; the assumed range is either 0.03–0.06 ( > 0, first three columns), or zero ( = 0, last three columns). AF, AB, EB refer to the asymptotic frequentist, approximate Bayesian, and exact Bayesian 10% intervals.

From: Interval estimation of genetic susceptibility for retrospective case-control studies

 

> 0

= 0

Interval

AF

AB

EB

AF

AB

EB

n = m = 10

      

Av. Length

0.375

0.308

0.394

0.371

0.303

0.391

Coverage

0.941

0.889

0.868

0.913

0.889

0.868

n = m = 50

      

Av. Length

0.154

0.144

0.155

0.143

0.134

0.145

Coverage

0.929

0.924

0.920

0.902

0.898

0.895

n = m = 100

      

Av. Length

0.110

0.107

0.110

0.096

0.093

0.097

Coverage

0.945

0.946

0.939

0.900

0.896

0.900

n = m = 500

      

Av. Length

0.067

0.067

0.066

0.041

0.041

0.041

Coverage

0.993

0.993

0.992

0.897

0.899

0.900