Skip to main content

Table 2 Parameter estimates of genotype and age group specific penetrances per 100,000, allele frequency, and transmission distortion under the two models: (M1) transmission probability fixed to 0.5 and (M2) transmission distortion estimated.

From: Increasing incidence of Type 1 diabetes – role for genes?

 

M1

M2

Parameter

Estimate

Estimate

20.737

5.301

37.372

17.777

43.812

37.861

32.167

5.301

105.522

37.861

105.522

37.861

32.167

93.123

390.694

93.123

390.694

93.123

0.001

0.124

τ

0.500

0.998

-2*log-likelihood

40431.68

40663.30