Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis

Table 6 Comparison of SNP allele frequencies of the studied Caucasian sample with the data on Hispanics from databases and literature

Gene	SNP	Database or references	Data from a database or reference		Caucasians^a		P
			Frequency^b	n	Frequency	n
ER-α	12	dbSNP	0.239	23	0.218	1,859	1.00
	15	dbSNP	0.196	23	0.203	1,863	1.00
IL-6	16	dbSNP	0.795	22	0.434	1,860	<0.01
TGF-ß1	26	dbSNP	0.413	23	0.311	1,840	0.36
UCP3	33	[73]	0.00	27	0.000	295	1.00
	36	[73]	0.02	27	0.000	295	1.00
VDR	41	dbSNP	0.348	23	0.408	1,859	0.83

For gene abbreviations and SNP designations see Table 1. ^aPresent study. ^bFrequency of the allele corresponding to a minor allele in the present study.

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