TY - JOUR AU - Zhou, D. AU - Salnikow, K. AU - Costa, M. PY - 1998 DA - 1998// TI - Cap43, a novel gene specially induced by Ni2+ compounds JO - Cancer Res VL - 58 ID - Zhou1998 ER - TY - JOUR AU - Salnikow, K. AU - Blagosklonny, M. V. AU - Ryan, H. AU - Johnson, R. AU - Costa, M. PY - 2000 DA - 2000// TI - Carcinogenic nickel induces genes involved with hypoxic stress JO - Cancer Res VL - 60 ID - Salnikow2000 ER - TY - JOUR AU - Piquemal, D. AU - Joulia, D. AU - Balaguer, P. AU - Basset, A. AU - Marti, J. AU - Commes, T. PY - 1999 DA - 1999// TI - Differential expression of the RTP/Drg1/Ndr1 gene product in proliferating and growth arrested cells JO - Biochim Biophys Acta VL - 1450 UR - https://doi.org/10.1016/S0167-4889(99)00056-7 DO - 10.1016/S0167-4889(99)00056-7 ID - Piquemal1999 ER - TY - JOUR AU - Kokame, K. AU - Kato, H. AU - Miyata, T. PY - 1996 DA - 1996// TI - Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes JO - J Biol Chem VL - 271 UR - https://doi.org/10.1074/jbc.271.47.29659 DO - 10.1074/jbc.271.47.29659 ID - Kokame1996 ER - TY - STD TI - Pubmed OMIM Database, Gene #: 605262, Gene Function. [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605262] UR - http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605262 ID - ref5 ER - TY - JOUR AU - Zhou, D. AU - Costa, M. PY - 1997 DA - 1997// TI - Identification and cloning of a gene specifically induced by nickel (II) exposure JO - Toxicologist VL - 36 ID - Zhou1997 ER - TY - CHAP AU - Zhou, D. PY - 1997 DA - 1997// TI - Identification and characterization of a novel gene specifically induced by nickel (II) BT - Ph.D. Thesis. New York University, New York ID - Zhou1997 ER - TY - CHAP AU - Salnikow, K. AU - Zhou, D. AU - Kluz, T. AU - Wang, C. AU - Costa, M. ED - Sarkar, B. PY - 1999 DA - 1999// TI - Cap43: a new gene induced by a rise in free intracellular Ca2+ following Ni2+ exposure BT - In: Metals and Genetics PB - New York CY - Plenum Publishing Corp UR - https://doi.org/10.1007/978-1-4615-4723-5_9 DO - 10.1007/978-1-4615-4723-5_9 ID - Salnikow1999 ER - TY - JOUR AU - Salnikow, K. AU - Su, W. AU - Blagosklonny, M. V. AU - Costa, M. PY - 2000 DA - 2000// TI - Carcinogenic metals induce hypoxia-inducible factor-stimulated transcription by reactive oxygen species-independent mechanism JO - Cancer Res VL - 60 ID - Salnikow2000 ER - TY - JOUR AU - Namiki, A. AU - Brogi, E. AU - Kearney, M. AU - Kim, E. A. AU - Wu, T. AU - Coffinhal, T. AU - Varticovski, L. AU - Isner, J. M. PY - 1995 DA - 1995// TI - Hypoxia induces vascular endothelial growth factor in cultured human endothelial cells JO - J Biol Chem VL - 270 UR - https://doi.org/10.1074/jbc.270.52.31189 DO - 10.1074/jbc.270.52.31189 ID - Namiki1995 ER - TY - JOUR AU - Huang, L. E. AU - Ho, V. AU - Arany, Z. AU - Krainc, C. AU - Galson, D. AU - Tendler, D. AU - Livingstone, D. M. AU - Bunn, H. F. PY - 1997 DA - 1997// TI - Erythropoietin gene regulation depends on heme-depending oxygen sensing and assembly of interacting transcription factors JO - Kidney Int VL - 51 UR - https://doi.org/10.1038/ki.1997.76 DO - 10.1038/ki.1997.76 ID - Huang1997 ER - TY - JOUR AU - Graven, K. K. AU - McDonald, R. J. AU - Farber, H. W. PY - 1998 DA - 1998// TI - Hypoxic regulation of endothelial glyceraldehyde-3-phosohate dehydrogenase JO - Am J Physiol VL - 274 ID - Graven1998 ER - TY - JOUR AU - Semenza, G. L. AU - Roth, P. H. AU - Fang, H. -. M. AU - Wang, L. W. PY - 1994 DA - 1994// TI - Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1 JO - J Biol Chem VL - 269 ID - Semenza1994 ER - TY - JOUR AU - Wang, G. L. AU - Jiang, B. -. H. AU - Rue, E. A. AU - Semenza, G. L. PY - 1995 DA - 1995// TI - Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension JO - Proc Natl Acad Sci USA VL - 92 UR - https://doi.org/10.1073/pnas.92.12.5510 DO - 10.1073/pnas.92.12.5510 ID - Wang1995 ER - TY - JOUR AU - Ryan, H. E. AU - Poloni, M. AU - McNulty, W. AU - Elson, D. AU - Gassmann, M. AU - Arbeit, J. M. AU - Johnson, R. S. PY - 2000 DA - 2000// TI - Hypoxia-inducible factor-1α is a positive factor in solid tumour growth JO - Cancer Res VL - 60 ID - Ryan2000 ER - TY - JOUR AU - Ivan, M. AU - Kondo, K. AU - Yang, H. AU - Kim, W. AU - Valiando, J. AU - Ohh, M. AU - Salic, A. AU - Asara, J. M. AU - Lane, W. S. AU - Kaelin, W. G. PY - 2001 DA - 2001// TI - HIFα targeted for VHL-Mediated Destruction by proline hydroxylation: Implications for O2 sensing JO - Science VL - 292 UR - https://doi.org/10.1126/science.1059817 DO - 10.1126/science.1059817 ID - Ivan2001 ER - TY - JOUR AU - Jaakkola, P. AU - Mole, D. R. AU - Tian, Y. -. M. AU - Wilson, M. I. AU - Gielbert, J. AU - Gaskell, S. J. AU - von Kriegsheim, A. AU - Hebestreit, H. F. AU - Mukherji, M. AU - Schofield, C. J. AU - Maxwell, P. H. AU - Pugh, C. W. AU - Ratcliffe, P. J. PY - 2001 DA - 2001// TI - Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation JO - Science VL - 292 UR - https://doi.org/10.1126/science.1059796 DO - 10.1126/science.1059796 ID - Jaakkola2001 ER - TY - JOUR AU - Mahon, P. C. AU - Hirota, K. AU - Semenza, G. L. PY - 2001 DA - 2001// TI - FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity JO - Genes Dev VL - 15 UR - https://doi.org/10.1101/gad.924501 DO - 10.1101/gad.924501 ID - Mahon2001 ER - TY - JOUR AU - Lando, D. AU - Peet, D. J. AU - Gorman, J. J. AU - Whelan, D. A. AU - Whitelaw, M. L. AU - Bruick, R. K. PY - 2002 DA - 2002// TI - FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor JO - Genes Dev VL - 16 UR - https://doi.org/10.1101/gad.991402 DO - 10.1101/gad.991402 ID - Lando2002 ER - TY - JOUR AU - McNeill, L. A. AU - Hewitson, K. S. AU - Claridge, T. D. AU - Seibel, J. F. AU - Horsfall, L. E. AU - Schofield, C. J. PY - 2002 DA - 2002// TI - Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803 JO - Biochem J VL - 367 UR - https://doi.org/10.1042/bj20021162 DO - 10.1042/bj20021162 ID - McNeill2002 ER - TY - JOUR AU - Lee, C. AU - Kim, S. J. AU - Jeong, D. G. AU - Lee, S. M. AU - Ryu, S. E. PY - 2003 DA - 2003// TI - Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.M210385200 DO - 10.1074/jbc.M210385200 ID - Lee2003 ER - TY - JOUR AU - Ema, M. AU - Hirota, K. AU - Mimura, J. AU - Abe, H. AU - Yodoi, J. AU - Sogawa, K. AU - Poellinger, L. AU - Fujii-Kuriyama, Y. PY - 1999 DA - 1999// TI - Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300 JO - EMBO J VL - 18 UR - https://doi.org/10.1093/emboj/18.7.1905 DO - 10.1093/emboj/18.7.1905 ID - Ema1999 ER - TY - JOUR AU - Kung, A. L. AU - Wang, S. AU - Klco, J. M. AU - Kaelin, W. G. AU - Livingston, D. M. PY - 2000 DA - 2000// TI - Suppression of tumour growth through disruption of hypoxia-inducible transcription JO - Nat Med VL - 6 UR - https://doi.org/10.1038/82146 DO - 10.1038/82146 ID - Kung2000 ER - TY - JOUR AU - Gu, J. AU - Milligan, J. AU - Huang, L. E. PY - 2001 DA - 2001// TI - Molecular mechanism of hypoxia-inducible factor 1alpha-p300 interaction. A leucine-rich interface regulated by a single cysteine JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M009522200 DO - 10.1074/jbc.M009522200 ID - Gu2001 ER - TY - JOUR AU - Semenza, G. L. PY - 1998 DA - 1998// TI - Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasis JO - J Lab Clin Med VL - 131 UR - https://doi.org/10.1016/S0022-2143(98)90091-9 DO - 10.1016/S0022-2143(98)90091-9 ID - Semenza1998 ER - TY - JOUR AU - Lok, C. N. AU - Ponka, P. PY - 1999 DA - 1999// TI - Identification of a hypoxia response element in the transferrin receptor gene JO - J Biol Chem VL - 274 UR - https://doi.org/10.1074/jbc.274.34.24147 DO - 10.1074/jbc.274.34.24147 ID - Lok1999 ER - TY - JOUR AU - Cangul, H. AU - Salnikow, K. AU - Yee, H. AU - Zagzag, D. AU - Commes, T. AU - Costa, M. PY - 2002 DA - 2002// TI - Enhanced overexpression of an HIF-1/hypoxia-related protein in cancer cells JO - Environ Health Perspect VL - 110 UR - https://doi.org/10.1289/ehp.02110s5783 DO - 10.1289/ehp.02110s5783 ID - Cangul2002 ER - TY - JOUR AU - Madan, A. AU - Curtin, P. T. PY - 1993 DA - 1993// TI - A 24-base-pair sequence 3' to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer JO - Proc Natl Acad Sci VL - 90 UR - https://doi.org/10.1073/pnas.90.9.3928 DO - 10.1073/pnas.90.9.3928 ID - Madan1993 ER - TY - JOUR AU - Schofield, C. J. AU - Zhang, Z. PY - 1999 DA - 1999// TI - Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes JO - Curr Opin Struct Biol VL - 9 UR - https://doi.org/10.1016/S0959-440X(99)00036-6 DO - 10.1016/S0959-440X(99)00036-6 ID - Schofield1999 ER - TY - CHAP AU - Kivirikko, K. I. AU - Myllyla, R. ED - Freeman, R. B. ED - Hawkins, H. C. PY - 1980 DA - 1980// BT - Enzymology of Posttranslational Modification of Proteins PB - London CY - Academic Press ID - Kivirikko1980 ER - TY - JOUR AU - Zhu, H. AU - Bunn, H. F. PY - 1999 DA - 1999// TI - Oxygen sensing and signaling: impact on the regulation of physiologically important genes JO - Respir Physiol VL - 115 UR - https://doi.org/10.1016/S0034-5687(99)00024-9 DO - 10.1016/S0034-5687(99)00024-9 ID - Zhu1999 ER - TY - JOUR AU - Zhu, H. AU - Bunn, H. F. PY - 2001 DA - 2001// TI - How do cells sense oxygen? JO - Science VL - 292 UR - https://doi.org/10.1126/science.1060849 DO - 10.1126/science.1060849 ID - Zhu2001 ER - TY - JOUR AU - Lando, D. AU - Peet, D. J. AU - Whelan, D. A. AU - Gorman, J. J. AU - Whitelaw, M. L. PY - 2002 DA - 2002// TI - Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch JO - Science VL - 295 UR - https://doi.org/10.1126/science.1068592 DO - 10.1126/science.1068592 ID - Lando2002 ER - TY - JOUR AU - Lachat, P. AU - Shaw, P. AU - Gebhard, S. AU - van Belzen, N. AU - Chaubert, P. AU - Bosman, F. T. PY - 2002 DA - 2002// TI - Expression of NDRG1, a differentiation-related gene, in human tissues JO - Histochem Cell Biol VL - 118 UR - https://doi.org/10.1007/s00418-002-0460-9 DO - 10.1007/s00418-002-0460-9 ID - Lachat2002 ER - TY - JOUR AU - Arnould, T. AU - Michiels, C. AU - Alexandre, I. AU - Remacle, J. PY - 1992 DA - 1992// TI - Effect of hypoxia upon intracellular calcium concentration of human endothelial cells JO - J Cell Physiol VL - 152 UR - https://doi.org/10.1002/jcp.1041520127 DO - 10.1002/jcp.1041520127 ID - Arnould1992 ER - TY - JOUR AU - Hampl, V. AU - Cornfield, D. N. AU - Cowan, N. J. AU - Archer, S. L. PY - 1995 DA - 1995// TI - Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells JO - Eur Respir J VL - 8 ID - Hampl1995 ER - TY - JOUR AU - Salnikow, K. AU - Kluz, T. AU - Costa, M. AU - Piquemal, D. AU - Demidenko, Z. N. AU - Xie, K. AU - Blagosklonny, M. V. PY - 2002 DA - 2002// TI - The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia JO - Mol Cell Biol VL - 22 UR - https://doi.org/10.1128/MCB.22.6.1734-1741.2002 DO - 10.1128/MCB.22.6.1734-1741.2002 ID - Salnikow2002 ER - TY - JOUR AU - Stein, I. M. AU - Neeman, M. AU - Shweiki, D. AU - Itin, A. AU - Keshet, E. PY - 1995 DA - 1995// TI - Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and co-regulation with other ischemia-induced genes JO - Mol Cell Biol VL - 15 UR - https://doi.org/10.1128/MCB.15.10.5363 DO - 10.1128/MCB.15.10.5363 ID - Stein1995 ER - TY - JOUR AU - Levy, A. P. AU - Levy, N. S. AU - Goldberg, M. A. PY - 1996 DA - 1996// TI - Post-transcriptional regulation of vascular endothelial growth factor by hypoxia JO - J Biol Chem VL - 271 UR - https://doi.org/10.1074/jbc.271.5.2746 DO - 10.1074/jbc.271.5.2746 ID - Levy1996 ER - TY - JOUR AU - Masuda, K. AU - Ono, M. AU - Okamoto, M. AU - Morikawa, W. AU - Otsubo, M. AU - Migita, T. AU - Tsuneyoshi, M. AU - Okuda, H. AU - Shun, T. AU - Naito, S. AU - Kuwano, M. PY - 2003 DA - 2003// TI - Down regulation of Cap43 gene by von Hippel-Lindau tumour suppressor protein in human renal cancer cells JO - Int J Cancer VL - 105 UR - https://doi.org/10.1002/ijc.11152 DO - 10.1002/ijc.11152 ID - Masuda2003 ER - TY - JOUR AU - Zhong, H. AU - De Marzo, A. M. AU - Laughner, E. AU - Lim, M. AU - Hilton, D. A. AU - Zagzag, D. AU - Buechler, P. AU - Isaacs, W. B. AU - Semenza, G. L. AU - Simons, J. W. PY - 1999 DA - 1999// TI - Overexpression of hypoxia-inducible factor-1 α in common human cancers and their metastases JO - Cancer Res VL - 59 ID - Zhong1999 ER - TY - JOUR AU - van Belzen, N. AU - Dinjens, W. N. M. AU - Diesveld, M. P. G. AU - Groen, N. A. AU - van der Made, A. C. Z. AU - Nozawa, Y. AU - Vliestra, R. AU - Trapman, J. AU - Bosman, F. T. PY - 1997 DA - 1997// TI - A novel gene which is up regulated during colon cell differentiation and down regulated in colo-rectal neoplasms JO - Lab Invest VL - 77 ID - van Belzen1997 ER - TY - JOUR AU - Hockel, M. AU - Vaupel, P. PY - 2001 DA - 2001// TI - Tumour hypoxia: definitions and current clinical, biologic, and molecular aspects JO - J Natl Cancer Inst VL - 93 UR - https://doi.org/10.1093/jnci/93.4.266 DO - 10.1093/jnci/93.4.266 ID - Hockel2001 ER - TY - JOUR AU - Ryan, H. E. AU - Lo, J. AU - Johnson, R. S. PY - 1998 DA - 1998// TI - HIF-1α is required for solid tumour formation and embryonic vascularization JO - EMBO J VL - 17 UR - https://doi.org/10.1093/emboj/17.11.3005 DO - 10.1093/emboj/17.11.3005 ID - Ryan1998 ER -