A multilocus likelihood approach to joint modeling of linkage, parental diplotype and gene order in a full-sib family

Table 3 Comparison of the estimation of the linkage and parental diplotype between two dominant markers in a full-sib family of n = 100 from the traditional and our model

	Traditional model				Our model
	cis × cis	cis × trans	trans × cis	trans × trans
Data simulated from cis × cis
Correct diplotype combination	Correct	Incorrect	Incorrect	Incorrect
Log-likelihood^a	-46.2	-92.3	-92.3	-46.2
under each diplotype combination	0.1981 ± 0.0446	0.5000 ± 0.0000	0.5000 ± 0.0000	0.8018 ± 0.0446
Estimated diplotype combination	Selected
under correct diplotype combination	0.1981 ± 0.0446				0.1982 ± 0.0446
Diplotype probability for parent P ()					1.0000 ± 0.0000
Diplotype probability for parent Q ()					1.0000 ± 0.0000
Data simulated from trans × trans
Correct diplotype combination	Incorrect	Incorrect	Incorrect	Correct
Log-likelihood^a	-89.6	-89.6	-89.6	-89.6
under each diplotype combination	0.8573 ± 0.1253	0.0393 ± 0.0419	0.0393 ± 0.0419	0.1426 ± 0.1253
Estimated diplotype combination		Selected	Selected
under correct diplotype combination				0.1426 ± 0.1253	0.1428 ± 0.1253
Diplotype probability for parent P ()					0.0000 ± 0.0000
Diplotype probability for parent Q ()					0.0000 ± 0.0000

^aThe log-likelihood values given here are those from one random simulation for each diplotype combination by the traditional model.

ISSN: 2730-6844