Table 2 Results of logistic regression analysis for the association of PON1 Q192R genotype with coronary heart disease (CHD) in the British Women's Heart and Health study N = 3,266
Genotype | OR (95% CI) for myocardial infarction [N = 111] | OR (95% CI) for angina [N = 369] | OR (95% CI) for any CHD [N = 480] |
|---|---|---|---|
Dominant model | |||
1 | 1 | 1 | |
QR or RR | 1.13 (0.76, 1.70) p = 0.49 | 1.04 (0.84, 1.27) p = 0.64 | 1.03 (0.89, 1.21) p = 0.62 |
Recessive model | |||
QQ or QR | 1 | 1 | 1 |
RR | 1.42 (0.76, 2.64) p = 0.26 | 0.67 (0.44, 1.01) p = 0.06 | 0.79 (0.59, 1.05) p = 0.11 |
Per allele | |||
1 | 1 | 1 | |
QR | 1.09 (0.72, 1.67) | 1.12 (0.91, 1.39) | 1.09 (0.92, 1.28) |
RR | 1.45 (0.76, 2.78) | 0.70 (0.46, 1.08) | 0.82 (0.60, 1.11) |
Per allele | 1.04 (0.98, 1.10) p = 0.24 | 0.98 (0.93, 1.02) p = 0.11 | 0.98 (0.95, 1.01) p = 0.16 |