Skip to main content

Table 4 List of genes grouped under gene ontology molecular functions that showed changes in the discordant monozygotic (MZ) twin pairs but not the concordant pair.

From: Variations in genome-wide gene expression in identical twins – a study of primary osteoblast-like culture from female twins discordant for osteoporosis

Probe Set ID Gene Name Fold changed Gene Symbol
5125 Cytokine activity in 2A/2B decrease
204926_at inhibin, beta A (activin A, activin AB alpha polypeptide) 2.1 INHBA
205067_at interleukin 1, beta 4.3 IL1B
205476_at* chemokine (C-C motif) ligand 20 3.0 CCL20
205767_at Epiregulin 3.3 EREG
206569_at interleukin 24 3.3 IL24
210557_x_at colony stimulating factor 1 (macrophage) 2.1 CSF1
211839_s_at colony stimulating factor 1 (macrophage) 2.8 CSF1
221577_x_at* prostate differentiation factor 2.3 PLAB
39402_at interleukin 1, beta 4.0 IL1B
8083 Growth factor activity in 2A/2B decrease
204926_at inhibin, beta A (activin A, activin AB alpha polypeptide) 2.1 INHBA
205067_at interleukin 1, beta 4.3 IL1B
205767_at Epiregulin 3.3 EREG
210557_x_at colony stimulating factor 1 (macrophage) 2.1 CSF1
211839_s_at colony stimulating factor 1 (macrophage) 2.8 CSF1
221577_x_at* prostate differentiation factor 2.3 PLAB
39402_at interleukin 1, beta 4.0 IL1B
5194 Cell adhesion molecular activity in 2A/2B increase
202877_s_at complement component 1, q subcomponent, receptor 1 2.0 C1QR1
203477_at collagen, type XV, alpha 1 2.0 COL15A1
204677_at** cadherin 5, type 2, VE-cadherin (vascular epithelium) 5.7 CDH5
208983_s_at** platelet/endothelial cell adhesion molecule (CD31 antigen) 3.5 PECAM1
212713_at microfibrillar-associated protein 4 3.7 MFAP4
3700 Transcription factor activity in 3A/3B decrease
207034_s_at GLI-Kruppel family member GLI2 2.0 GLI2
207147_at distal-less homeo box 2 2.6 DLX2
208003_s_at nuclear factor of activated T-cells 5, tonicity-responsive 3.3 NFAT5
208859_s_at alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) 2.8 ATRX
209088_s_at ubinuclein 1 2.1 UBN1
212420_at E74-like factor 1 (ets domain transcription factor) 2.1 ELF1
215698_at retinoblastoma binding protein 2 2.1 RBBP2
3700 Transcription factor activity in 3A/3B increase
205991_s_at paired mesoderm homeo box 1 2.0 PMX1
207001_x_at delta sleep inducing peptide, immunoreactor 2.0 DSIPI
207558_s_at paired-like homeodomain transcription factor 2 3.7 PITX2
208502_s_at paired-like homeodomain transcription factor 1 8.6 PITX1
210135_s_at short stature homeobox 2 7.5 SHOX2
221950_at empty spiracles homolog 2 (Drosophila) 4.3 EMX2
5194 Cell adhesion activity in 3A/3B increase
204677_at cadherin 5, type 2, VE-cadherin (vascular epithelium) 3.5 CDH5
208983_s_at platelet/endothelial cell adhesion molecule (CD31 antigen) 2.6 PECAM1
  1. * Also show decrease in 1A/1B pair but the changes were less than 2 folds ** Also show increase in 3A/3B pair