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Table 3 Numbers of probe sets showing decrease or increase of the three most frequent gene ontology (GO) molecular function in each pair's comparison. 2A/2B and 3A/3B are the discordant pair for BMD, and 1A/1B is the concordant pair.

From: Variations in genome-wide gene expression in identical twins – a study of primary osteoblast-like culture from female twins discordant for osteoporosis

  

GO molecular function*

No of probe sets

1A/1B

Decrease**

All

417

  

5488

159

  

3824

91

  

4871

85

 

Increase**

All

283

  

5488

111

  

3824

69

  

4871

45

2A/2B

Decrease

All

90

  

5488

35

  

4871

20

  

3824

17

 

Increase

All

45

  

5488

18

  

3824

6

  

4871

6

3A/3B

Decrease

All

133

  

5488

53

  

3824

27

  

4871

15

 

Increase

All

59

  

5488

23

  

3824

11

  

4871

10

  1. * Gene ontology molecular function terms are: 5488 – binding activity; 3824 – enzyme activity and 4871 – signal transducer activity. ** Decrease or increase is referred to 1B, 2B and 3B who had higher BMD than 1A, 2A and 3A respectively.