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Table 3 Familial correlations from combined data.

From: Familial aggregation of components of the multiple metabolic syndrome in the Framingham Heart and Offspring Cohorts: Genetic Analysis Workshop Problem 1

  

1971 – 1975

  

1984–1987

  

Component

Relationship

N (pairs)

Corr.

95% CI

N (pairs)

Corr.

95% CI

Plasma Total Cholesterol

Sibling

2522

0.26

(0.21, 0.32)

1595

0.25

(0.18, 0.32)

 

Parent-Child

2225

0.21

(0.16, 0.27)

1005

0.14

(0.06, 0.21)

 

Avuncular

1527

0.05

(-0.02, 0.13)

676

0.00

(-0.09, 0.10)

 

Cousin

1566

0.03

(-0.06, 0.11)

948

-0.04

(-0.13, 0.05)

 

Spousal

302

0.19

(0.08, 0.30)

127

0.13

(-0.04, 0.30)

HDL Cholesterol

Sibling

   

1588

0.27

(0.20, 0.34)

 

Parent-Child

   

999

0.24

(0.16, 0.31)

 

Avuncular

   

671

0.13

(0.02, 0.23)

 

Cousin

   

940

0.06

(-0.04, 0.17)

 

Spousal

   

126

0.07

(-0.11, 0.25)

Systolic Blood Pressure

Sibling

2576

0.18

(0.13, 0.24)

1756

0.17

(0.11, 0.23)

 

Parent-Child

2278

0.07

(0.02, 0.12)

1287

0.06

(-0.01, 0.12)

 

Avuncular

1573

0.04

(-0.02, 0.10)

857

0.08

(0.00, 0.16)

 

Cousin

1591

-0.05

(-0.12, 0.01)

1017

-0.05

(-0.12, 0.03)

 

Spousal

306

0.07

(-0.04, 0.19)

167

0.18

(0.03, 0.33)

Body Mass Index

Sibling

2580

0.25

(0.19, 0.31)

1675

0.24

(0.18, 0.30)

 

Parent-Child

2274

0.21

(0.16, 0.26)

1196

0.17

(0.10, 0.24)

 

Avuncular

1574

0.01

(-0.06, 0.08)

808

0.03

(-0.06, 0.12)

 

Cousin

1598

-0.03

(-0.11, 0.04)

963

0.01

(-0.08, 0.10)

 

Spousal

303

0.16

(0.05, 0.27)

160

0.34

(0.20, 0.47)