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Table 3 Regions with at least suggestive evidence under one analysis.A

From: Comparison of linkage analysis methods for genome-wide scanning of extended pedigrees, with application to the TG/HDL-C ratio in the Framingham Heart Study

 

LINKAGE

GH

MCLINK

SOLAR

Chromosome

22

5

2

7

Full Sample LOD

3.37 (2pt)

2.65 (mpt)

2.29 (mpt)

2.67 (2pt)

cM

21 cM

125 cM

201 cM

163 cM

No. peds linked

9

3

11

5

sumLOD

6.28 (mpt)

3.16 (mpt)

7.23 (mpt)

3.01 (mpt)

1-LOD size

13 cM

15 cM

21 cM

15 cM

1-LOD boundaries

12–25 cM

117–132 cM

192–213 cM

162–177 cM

Recomb size

27 cM

13 cM

18 cM

9 cM

Recomb boundaries

0–27 cM

114–127 cM

201–219 cM

161–170 cM

No. peds (L,R bnds)

(0, 3)

(1, 1)

(2, 3)

(1, 1)