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Table 1 Regions with suggestive or significant evidence of linkage to SBP

From: Genome-wide linkage scan for genes affecting longitudinal trends in systolic blood pressure

Trait

WeightsA

Chromosome: Region

Marker Name(s)

MaximumB -log10 (p-value)

SBP mean (b1)

t, c

5: 24–36 cM

GATA3E10

5.09 at 32 cM

SBP mean (b1)

t, m, c

12: 68–82 cM

GGAT2G06

6.54 at 78 cM

SBP mean (b1)

t, m, c

15: 111–134 cM

GATA22F01, GATA27A03

6.68 at 129 cM

SBP mean (b1)

c

16: 133–139 cM

 

4.34 at 137 cM

SBP mean (b1)

t, c

17: 107–119 cM

GATA28D11

5.32 at 109 cM

SBP slope (b2)

m

20: 70–78 cM

GATA47F05

4.38 at 72 cM

SBP curvature (b3)

u, t, m, c

20: 70–82 cM

GATA47F05

5.55 at 74 cM

SBP mean (b1)

m, c

22: 35–48 cM

GATA6F05, GATA11B12

4.85 at 38 cM

  1. Au, unweighted model; t, trait weights; m, marker weights; c, combined weights. BReported maximum -log p-values refer to the corresponding weighting scheme indicated in bold.