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Table 2 Bayesian approach result for Replicate 54

From: Linkage analysis of the simulated data – evaluations and comparisons of methods

 

Model

Marginalc

Joint

No.

Freq.a

Penetrancesb

1

1

2

2

1

0.2

0.05

0.50

0.70

1.00

42.2

0.92

38.5

0.92

46.3

2

0.1

0.10

0.50

0.70

1.00

42.3

0.85

37.8

0.90

46.4

3

0.2

0.00

0.20

0.50

1.00

42.4

0.89

39.2

0.92

48.3

4

0.2

0.00

0.50

0.60

1.00

41.7

0.85

36.9

0.92

45.4

5

0.2

0.00

0.35

0.55

1.00

41.8

0.81

38.2

0.92

46.3

6

0.3

0.00

0.60

1.00

1.00

42.9

0.51

30.7

0.98

45.6

7

0.3

0.00

0.20

0.60

1.00

42.6

0.96

39.7

0.93

48.6

8

0.3

0.00

0.40

0.80

1.00

42.4

0.95

39.2

0.95

48.2

  1. aFreq., P(D), where D is disease allele. bPenetrances are for genotypes dd, Dd, DD, in that order. c and represent the estimated posterior probability of linkage and the corresponding position of the disease gene for the marginal analysis. Similar notations for joint analysis are used.