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Table 3 Genome Screen Results for AGE = 45

From: Identification of genes for complex disease using longitudinal phenotypes

Phenotype h2 n covar.A 1 3 5 7 9 11 13 15 17 19 21 false+
BMI AGE = 45 76.0 2674 g 0.3 0.1 1.1 0.6 1.2 1.3 20.2 0.5 1.0 0.2 0.1 1.5
  AUCB 76.2 2674 g 0.5 0.2 1.6 1.0 1.1 1.0 23.0 1.3 1.2 0.3 0.0 1.7
Chol AGE = 45 59.7 2650 g 1.6 0.4 0.1 1.0 1.2 3.4 0.9 3.2 0.4 0.3 1.7 1.2
  AUC 66.6 2650 a,g 1.3 0.7 0.1 0.5 0.7 4.9 0.6 3.4 0.2 0.3 1.4 1.2
Gluc AGE = 45 64.6 2412 - 1.0 0.9 22.2 0.3 1.9 0.5 0.0 0.1 0.4 0.1 0.1 1.3
  AUC 62.9 2412 a 1.3 1.0 25.1 0.3 1.7 1.2 0.0 0.0 0.9 0.3 0.0 3.1
HDL AGE = 45 65.4 1600 b,c,d,g 2.2 0.5 0.1 1.3 8.5 0.4 0.9 0.0 9.8 0.5 0.6 2.4
  AUC 66.1 1600 b,c,d,g 2.9 0.8 0.5 1.1 9.0 0.2 0.5 0.0 8.6 0.7 0.3 2.8
Height AGE = 45 73.7 2585 g 0.2 1.1 12.3 4.7 0.3 0.2 1.9 0.6 0.3 0.2 0.0 0.7
  AUC 75.0 2585 g 0.4 0.8 13.8 5.1 0.5 0.2 1.3 1.0 0.6 0.1 0.0 0.9
SBP AGE = 45 74.7 2411 a,b,c 0.5 0.8 2.0 1.5 1.1 0.1 1.2 3.6 0.3 1.2 21.1 2.1
  AUC 71.3 2411 a,b,c 0.7 2.4 2.7 3.0 0.7 0.0 1.4 5.3 0.3 0.8 26.8 1.9
Tg AGE = 45 53.2 1585 a,b,d,g 6.2 0.2 0.9 0.7 1.7 1.4 0.3 0.3 0.6 0.3 0.5 1.6
  AUC 51.9 1585 a,b,d,g 7.6 0.2 0.7 1.3 2.9 2.5 0.3 0.2 0.6 0.5 0.4 1.1
  1. ASignificant covariates employed in the linkage analysis (a, average age in study; b, body mass index; c, cigarettes per day; d, drinks, alcohol consumption, g, gender). BResults of the longitudinal data with only those individuals included in the cross-sectional design. Only odd chromosomes contain genes; even chromosomes are summarized as highest false positive (false+).
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