Age-stratified heritability estimation in the Framingham Heart Study families

BMC Genomic Data

Table 2 Heritability estimates for log transformed weight

	Trait: Weight (log)
Covariates	h²r ± SE	p-value	variance due to covariates (%)
Unadjusted
Age Group 40	0.51 ± 0.09	<0.0000001	-
Age Group 55	0.44 ± 0.10	<0.0000009	-
Age Group 70	0.45 ± 0.09	<0.0000001	-
Year 12 (age adjusted)	0.42 ± 0.10	<0.0000051	1
Gender, height
Age Group 40	0.60 ± 0.09	<0.0000001	46
Age Group 55	0.51 ± 0.09	<0.0000001	41
Age Group 70	0.51 ± 0.09	<0.0000001	35
Year 12 (age adjusted)	0.45 ± 0.10	<0.0000008	43
Gender, height, smoker
Age Group 40	0.58 ± 0.11	<0.0000001	44
Age Group 55	0.49 ± 0.11	<0.0000021	40
Age Group 70	0.49 ± 0.11	<0.0000025	33
Year 12 (age adjusted)	0.52 ± 0.10	<0.0000001	44
Gender, height, drinker
Age Group 40	0.63 ± 0.11	<0.0000001	45
Age Group 55	0.53 ± 0.11	<0.0000001	41
Age Group 70	0.52 ± 0.11	<0.0000003	36
Year 12 (age adjusted)	0.48 ± 0.12	<0.0000334	42
Gender, height, smoker, drinker
Age Group 40	0.63 ± 0.09	<0.0000001	31
Age Group 55	0.53 ± 0.09	<0.0000001	29
Age Group 70	0.51 ± 0.09	<0.0000001	21
Year 12 (age adjusted)	0.51 ± 0.12	<0.0000057	44

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