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Table 1 Results of the three different models for  C(SBP j *)A

From: Linkage analysis of longitudinal data

  

Model 1B

Model 2B

Model 3B

Gene

Variable

Rep. 43C

Rep. 43+47D

Rep. 43C

Rep. 43+47D

Rep. 43C

Rep. 43+47D

b34

I 1 E

6.08 F

5.05

7.26

7.39

7.34

7.62

  

(5.29)

(4.82)

(5.78)

(5.83)

(5.81)

(5.92)

b35

I 2

0.18

3.50

0.00

1.25

0.00

1.22

  

(0.90)

(4.01)

(-3.50)

(2.40)

(-3.47)

(2.37)

b36

I 3

0.00

0.00

0.00

0.00

0.00

0.00

  

(-10.49)

(-5.95)

(-0.53)

(-0.07)

(-0.55)

(-0.03)

s10

I 4

28.90

77.16

5.05

37.08

5.01

36.97

  

(11.53)

(18.84)

(4.82)

(13.06)

(4.80)

(13.04)

s11

I 5

28.15

68.26

27.66

34.02

27.86

34.35

  

(11.38)

(17.72)

(11.28)

(12.51)

(11.32)

(12.57)

s12

I 6

9.99

2.68

0.00

0.00

0.00

0.00

  

(6.78)

(3.51)

(-4.06)

(-7.69)

(-3.99)

(-7.59)

b5

U 1

6.67

6.48

1.78

0.04

1.73

0.04

  

(5.54)

(5.46)

(2.86)

(0.43)

(2.82)

(0.42)

b14

U 2

0.31

0.00

0.00

0.00

0.00

0.00

  

(1.19)

(-0.67)

(-6.62)

(-6.05)

(-6.63)

(-5.98)

b16

U 3

0.00

0.00

0.00

0.00

0.00

0.00

  

(-2.26)

(-3.60)

(-4.65)

(-2.71)

(-4.65)

(-2.67)

b18

U 4

0.00

0.00

0.00

0.00

0.00

0.02

  

(-3.08)

(-2.65)

(0.10)

(0.15)

(0.14)

(0.27)

b21

U 5

0.00

0.00

0.00

0.00

0.00

0.00

  

(-3.47)

(-6.72)

(-1.33)

(-2.01)

(-1.27)

(-1.93)

  1. A The mean-corrected cross-product for SBP*, which is residual of the observed SBP adjusted for effective nongenetic factors. B Model 1: independence model; Model 2: random effects model with two random effects; Model 3: random effects model with three random effects. C Simulations of one replicate (replicate 43 randomly chosen) consisting of the 99,714 observations from n = 2772 sib pairs. D Simulations of two replicates combined (replicate 43 and 47) for 199,536 observations from n = 5512 sib pairs. E I k (k = 1, ..., 6) is the number of alleles IBD at marker locus closest to a gene that determines SBP; U l (l = 1, ..., 5) denotes the number of alleles IBD at genes closest to five unlinked markers. F LOD scores (T-values). Values in bold type indicate significant variables: consider β k (or γ l ) > 0 if the LOD score ≥ 1.0 (i.e., T ≥ 2.14). The LOD score would be 0 when T < 0.