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Table 2 Max LOD scores reached in any replicate for genes affecting blood pressure for each phenotypic measure of SBP. Peak LOD within 20 cM of true location, using the sex averaged map.

From: Linkage analysis of cross-sectional and longitudinally derived phenotypic measures to identify loci influencing blood pressure

  

Phenotype

Gene

Location

Hypertension

SBP 1st exam

Model 1

Model 2

Model 3

Model 4

Gb34

Chr 5: 176.1 cM

NDA

1.8

ND

ND

ND

ND

Gb35

Chr 13: 85.2 cM

ND

ND

2.8

5.2

ND

ND

Gb36

Chr 7: 47.5 cM

ND

ND

ND

ND

ND

ND

Gb37

Chr 21: 29.1 cM

1.4

2.4

9.7

9.7

11

11.1

Gs10

Chr 21: 53.6 cM

1.4

2.4

10.4

10.3

11

11.1

Gs11

Chr 15: 4.5 cM

ND

ND

2.2

2.2

1.5

2.1

Gs12

Chr 21: 29.5 cM

1.4

2.4

9.7

9.7

11

11.1

False positives

 

1.5 (Chr 3)

2.7 (Chr 5)

1.7 (Chr 9)

1.7 (Chr 9)

 

1.4 (Chr 11)

  

1.6 (Chr 5)

1.5 (Chr 8)

2.3 (Chr 11)

2.3 (Chr 11)

  
  

1.4 (Chr 9)

3.4 (Chr 12)

    
  

1.6 (Chr 18)

     
  1. AND: no evidence of linkage detected at LOD > 1.3.
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BMC Genomic Data

ISSN: 2730-6844

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