Table 2 Summary of linked regions (P < 0.01) to SBP and HBP identified using different longitudinal measures
From: Genetic linkage analysis of longitudinal hypertension phenotypes using three summary measures
Method | Traits | Marker | Position (cM) | P-Value |
|---|---|---|---|---|
Individual time point (Cohort 2) | SBP | GATA70E11 (SBP1) | 46 | 0.00005 |
| Â | Â | GATA64A09 (SBP1) | 125 | 0.00782 |
| Â | Â | GATA64A09 (SBP2) | 125 | 0.00571 |
| Â | Â | GATA64A09 (SBP4) | 125 | 0.00279 |
| Â | HBP | GATA70E11 (HBP1) | 46 | 0.00691 |
| Â | Â | GGAA23C05 (HBP1) | 165 | 0.00767 |
Mean | SBP | GATA64A09 (Adjustment) | 125 | 0.00599 |
| Â | Â | GATA64A09 (No adjustment)A | 125 | 0.00492 |
| Â | HBP | GATA87G01 (Adjustment) | 94 | 0.00196 |
| Â | Â | GGAA2F11 (No adjustment) | 117 | 0.00407 |
| Â | Â | GATA64A09 (No adjustment) | 125 | 0.00618 |
Slope | SBP | Null | - | - |
Principal component (Cohort 2) | SBP | GATA87G01 (PRIN1) | 94 | 0.00010 |
| Â | Â | GATA64A09 (PRIN1) | 125 | 0.00190 |
| Â | HBP | GATA87G01 (PRIN1) | 94 | 0.00008 |
| Â | Â | GGAT1A4 (PRIN1) | 101 | 0.00140 |
| Â | Â | GATA115E01 (PRIN1) | 113 | 0.00070 |
| Â | Â | GGAA2F11 (PRIN1) | 117 | 0.00046 |
| Â | Â | GATA64A09 (PRIN1) | 125 | 0.00317 |
| Â | Â | GATA88F09 (PRIN2) | 4 | 0.00022 |
| Â | Â | Mfd187 (PRIN2) | 173 | 0.00915 |