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Figure 3 | BMC Genetics

Figure 3

From: Involvement of an SCFSlmb complex in timely elimination of E2F upon initiation of DNA replication in Drosophila

Figure 3

Reduction in Cul1 function causes apoptosis. (A) Wild-type third instar wing discs stained with acridine orange show very little cell death. (B) Discs with reduced Cul1 function due to mCul1 overexpression have a high level of cell death. (C) Small wing phenotype due to mCul1 expression (MS1096/Y;UAS-mCul1/+). (D) Partial suppression when the anti-apoptotic protein p35 is co-expressed (MS1096/Y;UAS-mCul1/UAS-p35).

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