Study of human SP-A, SP-B and SP-D loci: allele frequencies, linkage disequilibrium and heterozygosity in different races and ethnic groups

Table 4 Estimated three-locus haplotype frequencies and three-locus LD coefficients at B-18(A/C)-B1013(A/C)-B1580(C/T) in the seven ethnic groups

haplotype	Black Am		Nigerian		Mexican		German		Greek		Netherlands		White Am
	freq ^(a)	LD ^(b)	freq	LD	freq	LD	freq	LD	freq	LD	freq	LD	freq	LD
A A C	0	-0.011	0	-9.5E-4	0.007	0.007	0.012	0.008	0.011	0.011	0.019	0.038	0.017	-0.003
A A T	0	0.011	0.105	9.5E-4	0.014	-0.006	0.036	-0.008	0.018	-0.011	0	-0.038	0.038	0.003
A C C	0.198	0.011	0.231	9.5E-4	0.394	-0.006	0.273	-0.008	0.274	-0.011	0.465	-0.038	0.274	0.003
A C T	0.444	-0.011	0.325	-9.5E-4	0.124	0.006	0.274	0.008	0.248	0.011	0.249	0.038	0.249	-0.003
C A C	0.064	0.011	0	9.5E-4	0.159	-0.006	0.105	-0.008	0.145	-0.011	0.070	-0.038	0.132	0.003
C A T	0.063	-0.011	0.088	-9.5E-4	0.238	0.006	0.219	0.008	0.274	0.011	0.162	0.038	0.190	-0.003
C C C	0.074	-0.011	0.060	-9.5E-4	0.038	0.006	0.046	0.008	0.030	0.011	0.036	0.038	0.040	-0.003
C C T	0.157	0.011	0.191	9.4E-4	0.027	-0.006	0.035	-0.008	0	-0.011	0	-0.038	0.061	0.003

(a) Estimated three-locus haplotype frequency (b) Estimated three-locus linkage disequilibrium coefficient

ISSN: 2730-6844