Figure 7

DNA sequence traces of the mutations detected in exon 3, 4, and 5 of UNC93A.A) Sequence trace of the nucleotide variant c.452G>A in exon3, which confers a stop codon, in tumor T30 compared with its matched normal DNA. B) Sequence trace of the nucleotide variant c.625+1G>C at the 3' splice site of exon 4 in tumor T39, its matched normal and the variant band from the P³²-SSCP gel. C) Sequence trace of the nucleotide variant c.676C>T in exon 5, which confers a stop codon, in tumor T43 and its matched normal. Corresponding amino acids are shown at the top of each sequence trace.