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Figure 3 | BMC Genetics

Figure 3

From: SPE-8, a protein-tyrosine kinase, localizes to the spermatid cell membrane through interaction with other members of the SPE-8 group spermatid activation signaling pathway in C. elegans

Figure 3

Predicted structural model of SPE-8. The model was predicted by TM-align [11] using iTasser [12], and is based on the crystal structure of the human c-Abl Tyrosine Kinase protein. The highly significant structural predictions for the SH2 and kinase domains are indicated by red and blue labeling, respectively. The structures of the N- and C-terminal domains were predicted by iTasser without known protein models and are labeled in gray. The amino acids affected by the spe-8 mutations are indicated in stick form and labeled purple. Also shown are the predicted kinase active site in green and a proline rich domain in gold.

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BMC Genomic Data

ISSN: 2730-6844

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