Table 4 Predicted haplotype frequencies in the cohort using pyrosequencing or SSCP

-168 C > T

T

T

T

T

C

C

C

C

417

418

-181 A > C

A

A

C

C

A

A

C

C

204

418

-200 C > A

A

C

A

C

A

C

A

C

225

418

%

0.0

0.0

0.0

0.2

1.5

49.8

44.6

3.9

SSCP

SNP

Haplotype

C allele

Total alleles

-181 A > C

A

A

C

C

208

414

-200 C > A

A

C

A

C

205

414

%

0.2

49.5

50.2

0.0