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Table 2 Distribution of genotypes in the sample cohort

From: Detection of three closely located single nucleotide polymorphisms in the EAAT2 promoter: comparison of single-strand conformational polymorphism (SSCP), pyrosequencing and Sanger sequencing

Genotype -200C > A -181A > C -168C > T Number & proportion
1 C/C A/A C/C 42 (20%)
2 C/A A/C C/C 110 (53%)
3 A/A C/C C/C 34 (16%)
4 C/A C/C C/C 7 (3%)
5 A/A A/A C/C 4 (2%)
6 C/A A/A C/C 0
7a C/C A/C C/C 9 (4.5%)
7b C/C A/C C/T 1 (0.5%)
8 A/A A/C C/C 2 (1%)
9 C/C C/C C/C 0
n = 209
WT C = 0.54 A = 0.51 C = 0.997 Allele frequency
MT A = 0.46 C = 0.49 T = 0.002
  1. Genotypes were identified by pyrosequencing (n = 209) and confirmed by Sanger sequencing (n = 51). WT – wild type; MT – mutant.
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