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Table 2 Distribution of genotypes in the sample cohort

From: Detection of three closely located single nucleotide polymorphisms in the EAAT2 promoter: comparison of single-strand conformational polymorphism (SSCP), pyrosequencing and Sanger sequencing

Genotype

-200C > A

-181A > C

-168C > T

Number & proportion

1

C/C

A/A

C/C

42 (20%)

2

C/A

A/C

C/C

110 (53%)

3

A/A

C/C

C/C

34 (16%)

4

C/A

C/C

C/C

7 (3%)

5

A/A

A/A

C/C

4 (2%)

6

C/A

A/A

C/C

0

7a

C/C

A/C

C/C

9 (4.5%)

7b

C/C

A/C

C/T

1 (0.5%)

8

A/A

A/C

C/C

2 (1%)

9

C/C

C/C

C/C

0

n = 209

WT

C = 0.54

A = 0.51

C = 0.997

Allele frequency

MT

A = 0.46

C = 0.49

T = 0.002

  1. Genotypes were identified by pyrosequencing (n = 209) and confirmed by Sanger sequencing (n = 51). WT – wild type; MT – mutant.