SLC6A4STin2 VNTR genetic polymorphism is associated with tobacco use disorder, but not with successful smoking cessation or smoking characteristics: a case control study

Table 4 Associations between tobacco use disorder (TUD) characteristics and STin2 VNTR genotypes and allelic variants

Smoking parameters		Genotypes				Allelic variants
Smoking parameters			STin2 10/10	STin2 12/10	STin2 12/12	STin2.12	STin2.10
		n	P*	P*	P*	P*	P*
Onset of TUD (years)	14.81 (±3.91)	185	0.868	0.170	0.156	0.868	0.146
Duration of TUD (years)	33.59 (±11.28)	185	0.061	0.262	0.478	0.061	0.837
Cigarettes/day	22.28 (±13.45)	185	0.120	0.987	0.377	0.120	0.274
Pack-years	37.02 (±28.11)	185	0.017	0.617	0.239	0.017	0.247
Fagerström score	5.71 (±2.21)	185	0.361	0.670	0.591	0.361	0826
Attempts at smoking cessation	1, 2 or 3 attempts	86/67/32	0.948	0.852	0.728	0.948	0.739
Successful smoking cessation	Yes/no	64/185	0.658	0.858	0.612	0.658	0.630

Results are shown as mean ± SD.
*p values obtained in analyses of variance (all df = 1/183) or χ² tests (all df = 1).

ISSN: 2730-6844