|
Characteristics
|
No.
|
PTPROmethylation
|
|---|
| | |
Tumor tissue (%)
|
χ2
|
Pvalue
|
plasma (%)
|
χ2
|
Pvalue
|
|---|
|
Total
|
98
|
53 (54)
| | |
33 (34)
| | |
|
Age
| | | | | | | |
|
< 45 years
|
45
|
22 (49)
| | |
16 (36)
| | |
|
≥ 45 years
|
53
|
31 (59)
|
0.903
|
0.417
|
17 (32)
|
0.132
|
0.716
|
|
Nodal involvement
| | | | | | | |
|
Negative
|
61
|
27 (44)
| | |
18 (30)
| | |
|
Positive
|
37
|
26 (70)
|
6.273
|
0.014
|
15 (40)
|
0.935
|
0.334
|
|
Stage
| | | | | | | |
|
I/II
|
79
|
37 (47)
| | |
24 (30)
| | |
|
III
|
19
|
16 (84)
|
8.616
|
0.004
|
9 (47)
|
1.979
|
0.159
|
|
Histological type
| | | | | | | |
|
Non-ductal
|
23
|
12 (52)
| | |
7 (30)
| | |
|
Ductal
|
75
|
41 (55)
|
1.000
|
0.510
|
26 (35)
|
0.141
|
0.707
|
|
Tumour size
| | | | | | | |
|
≤20 mm
|
47
|
26 (55)
| | |
12 (26)
| | |
|
>20 mm
|
51
|
27 (53)
|
0.056
|
0.842
|
21 (40)
|
2.234
|
0.135
|
|
Histological grade
| | | | | | | |
|
Well/mod diff.
|
60
|
27 (45)
| | |
18 (30)
| | |
|
Poorly diff.
|
38
|
26 (68)
|
5.139
|
0.037
|
15 (40)
|
0.935
|
0.334
|
|
ER status
| | | | | | | |
|
Negative
|
24
|
16 (67)
| | |
10 (42)
| | |
|
Positive
|
74
|
37 (50)
|
2.027
|
0.167
|
23 (31)
|
0.909
|
0.340
|
|
PR status
| | | | | | | |
|
Negative
|
29
|
20 (69)
| | |
10 (35)
| | |
|
Positive
|
69
|
33 (48)
|
3.674
|
0.076
|
23 (33)
|
0.012
|
0.912
|
|
HER2 status
| | | | | | | |
|
Normal
|
51
|
19 (37)
| | |
12 (24)
| | |
|
Amplified
|
47
|
34 (72)
|
12.124
|
0.001
|
21 (46)
|
5.570
|
0.018
|
|
TP53 status
| | | | | | | |
|
Normal
|
59
|
30 (51)
| | |
17 (29)
| | |
|
Mutant
|
39
|
23 (59)
|
0.624
|
0.535
|
16 (41)
|
1.568
|
0.211
|
