Skip to main content

Table 4 List of SNPs with maternal-fetal genotype incompatibility effect associated with pPROM at α =0 . 005

From: Entropy-based selection for maternal-fetal genotype incompatibility with application to preterm prelabor rupture of membranes

Gene

Region

rs Number

P-value1

P-value2

MS

OR*

95 % CI

MGP

promoter

rs1800801

0.0006

0.0404

5

0.4175

[0.2343, 0.7438]

MMP14

exon 5

rs2236302

0.0014

0.0051

3

2.8013

[1.6398, 4.7854]

COL5A2

exon 48

rs6434312

0.0017

0.0045

10

0.5370

[0.3502, 0.8233]

ANGPT2

intron 6

rs2979671

0.0020

0.1450

1

0.2820

[0.0968, 0.8216]

ANGPT2

exon 4

rs3020221

0.0020

0.0259

1

0.2826

[0.0947, 0.8434]

TNFRSF1A

intron 4

rs1800692

0.0022

0.0968

7

2.1064

[1.3307, 3.3342]

AQP2

exon 4

629722653

0.0027

0.0271

2

2.8062

[1.4721, 5.3495]

CRHR1

intron 7

rs16940668

0.0038

0.0038

11

1.7365

[1.1605, 2.5986]

COL1A2

intron 46

rs13240759

0.0041

0.0041

9

0.5305

[0.3404, 0.8265]

GJA4

exon 2

rs1764389

0.0044

0.0044

11

1.6831

[1.1005, 2.5740]

HLA-E

exon 3

rs1264457

0.0046

0.6216

8

0.5468

[0.3491, 0.8566]

IL10

intron 4

rs5743627

0.0048

0.0048

11

1.3354

[0.8149, 2.1885]

COL4A2

intron 33

rs41315048

0.0049

0.0101

10

0.5709

[0.3718, 0.8767]

  1. 1: P-value obtained using the 2-step approach;
  2. 2: P-value obtained using the full model approach;
  3. *Odds ratio for the MFGI effect;
  4. MS: Model selection result;
  5. OR: Odds ratio;
  6. CI: Confidence interval.