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Table 4 List of SNPs with maternal-fetal genotype incompatibility effect associated with pPROM at α =0 . 005

From: Entropy-based selection for maternal-fetal genotype incompatibility with application to preterm prelabor rupture of membranes

Gene Region rs Number P-value1 P-value2 MS OR* 95 % CI
MGP promoter rs1800801 0.0006 0.0404 5 0.4175 [0.2343, 0.7438]
MMP14 exon 5 rs2236302 0.0014 0.0051 3 2.8013 [1.6398, 4.7854]
COL5A2 exon 48 rs6434312 0.0017 0.0045 10 0.5370 [0.3502, 0.8233]
ANGPT2 intron 6 rs2979671 0.0020 0.1450 1 0.2820 [0.0968, 0.8216]
ANGPT2 exon 4 rs3020221 0.0020 0.0259 1 0.2826 [0.0947, 0.8434]
TNFRSF1A intron 4 rs1800692 0.0022 0.0968 7 2.1064 [1.3307, 3.3342]
AQP2 exon 4 629722653 0.0027 0.0271 2 2.8062 [1.4721, 5.3495]
CRHR1 intron 7 rs16940668 0.0038 0.0038 11 1.7365 [1.1605, 2.5986]
COL1A2 intron 46 rs13240759 0.0041 0.0041 9 0.5305 [0.3404, 0.8265]
GJA4 exon 2 rs1764389 0.0044 0.0044 11 1.6831 [1.1005, 2.5740]
HLA-E exon 3 rs1264457 0.0046 0.6216 8 0.5468 [0.3491, 0.8566]
IL10 intron 4 rs5743627 0.0048 0.0048 11 1.3354 [0.8149, 2.1885]
COL4A2 intron 33 rs41315048 0.0049 0.0101 10 0.5709 [0.3718, 0.8767]
  1. 1: P-value obtained using the 2-step approach;
  2. 2: P-value obtained using the full model approach;
  3. *Odds ratio for the MFGI effect;
  4. MS: Model selection result;
  5. OR: Odds ratio;
  6. CI: Confidence interval.