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Table 2 Biologically plausible models of maternal-fetal genotype incompatibility

From: Entropy-based selection for maternal-fetal genotype incompatibility with application to preterm prelabor rupture of membranes

Model GC G m G o Scenario
1 M 1 AA Aa Mother has 1 more copy of allele A than the heterozygous offspring
2 M 2 Aa AA Offspring has 1 more copy of allele A than the heterozygous mother
3 M 3 Aa aa Mother has risk allele A that the offspring does not
4 M 4 aa Aa Offspring has risk allele A that the mother does not
5 M 1 AA Aa Mother-offspring pair has 3 copies of A allele
  M 2 Aa AA  
6 M 1 AA Aa Mother has 1 more copy of A allele
  M 3 Aa aa  
7 M 1 AA Aa Offspring has an allele that the mother does not
  M 4 aa Aa  
8 M 2 Aa AA Mother has an allele that the offspring does not
  M 3 Aa aa  
9 M 2 Aa AA Offspring has 1 more copy of the A allele
  M 4 aa Aa  
10 M 3 Aa aa Mother-offspring pair possesses 3 copies of allele a
  M 4 aa Aa  
11 M 1 AA Aa All possible mismatched maternal-fetal genotype combinations
  M 2 Aa AA  
  M 3 Aa aa  
  M 4 aa Aa  
  1. A: Minor allele;
  2. GC: Genotype combination.