Figure 3From: Tumor loci and their interactions on mouse chromosome 19 that contribute to testicular germ cell tumorsEpistatic interactions and testes abnormalities. (A) Epistatic interactions between regions. Bidirectional red arrows indicate positive epistatic interaction between regions I and IV and interaction of region I with (III.V). Bidirectional blue arrow indicates negative interaction between regions III and V. (B) TGCTs in congenic 3 mice. Specimens from left to right are: normal (N) pair of testes; tumor (T) in left testis and normal (N) right testis; normal left and tumor in right-testis; bilateral tumors in testes. (C) Abnormal testes from congenic 5 mice. Abnormal or small left testes (S) and normal (N) right testis. (D) Histological section of a small testis and (E) contralateral normal testis from congenic 5 mouse. In the small testes, spermatogenesis is arrested at specific stages. Few elongated spermatids are seen in the tubules.Back to article page