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Table 2 Association between phenotype of high myopia and genetic variants at 15q14 and 15q25 in the Han Chinese Population

From: Association study of 15q14 and 15q25 with high myopia in the Han Chinese population

Chr/Mb SNP [Minor Allele] Case MAF Allele Frequency OR P value Adjusted P* Genotype Frequency OR H-W P
15/35.0 rs634990[C] 0.483 C T     CC CT TT CC CT TT  
  HM cases   450(43.4%) 586(56.6%) 0.88(0.76-1.04) 0.27 0.54 102(19.7%) 246(47.5%) 170(32.8%) 0.82(0.63-1.07) 1.01(0.81-1.26) 1.15(0.91-1.45) 0.45
  Controls   858(46.6%) 984(53.4%)     212(23.0%) 434(47.1%) 275(29.9%)     0.11
15/79.5 rs8027411[G] 0.441 G T     GG GT TT GG GT TT  
  HM cases   396(38.7%) 626(61.3%) 0.78(0.66-0.91) 0.006 0.012 77(15.1%) 242(47.4%) 192(37.6%) 0.66(0.50-0.89) 0.99(0.80-1.23) 1.32(1.06-1.66) 0.96
  Controls   839(44.9%) 1029(55.1%)     197(21.1%) 445(47.6%) 292(31.3%)     0.26
  1. Adjusted P* is the P value modified by Bonferroni’s mutable tests correction.