Outcome | VDR | RXRG | Northern Finland Birth Cohort 1966 (NFBC66) | Twins UK | Meta-analysis of the results from NFBC66 and Twins UK | |||||
---|---|---|---|---|---|---|---|---|---|---|
SNP | SNP | |||||||||
N in analysis | Interaction Beta ± SE | Pinteraction | N in analysis | Interaction Beta ± SE | Pinteraction | Interaction Beta ± SE | Unadjusted Pinteraction(Adjusted Pinteraction*) | |||
Low density lipoprotein cholesterol | rs3847987 | rs283695 | 5,007 | −0.03 ± 0.03 | 0.26 | 1,555 | −0.08 ± 0.08 | 0.31 | −0.04 ± 0.03 | 0.16 |
rs11574143 | rs283695 | 4,990 | −0.02 ± 0.03 | 0.52 | 1,528 | −0.03 ± 0.08 | 0.75 | −0.02 ± 0.03 | 0.48 | |
Serum triglycerides | rs11574143 | rs17429123 | 5,155 | 0.01 ± 0.03 | 0.74 | 1,686 | 0.09 ± 0.06 | 0.13 | 0.03 ± 0.03 | 0.32 |
rs11574143 | rs10918172 | 5,131 | 0.03 ± 0.03 | 0.28 | 1,725 | 0.05 ± 0.05 | 0.37 | 0.04 ± 0.03 | 0.16 | |
rs3847987 | rs17429123 | 5,172 | 0.03 ± 0.03 | 0.28 | 1,730 | 0.08 ± 0.05 | 0.09 | 0.05 ± 0.02 | 0.08 | |
rs3847987 | rs10918172 | 5,148 | 0.05 ± 0.03 | 0.07 | 1,767 | 0.07 ± 0.05 | 0.14 | 0.06 ± 0.03 | 0.02 (0.17) | |
rs739837, rs2238136 | rs1273959 | 5,204 | −0.002 ± 0.03 | 0.95 | 1,883 | 0.01 ± 0.04 | 0.79 | 0.003 ± 0.03 | 0.91 | |
Waist hip ratio | rs2283342 | rs157872 | 4,707 | 0.002 ± 0.003 | 0.53 | 3,376 | −0.002 ± 0.004 | 0.62 | 0.001 ± 0.002 | 0.78 |