Interaction between allelic variations in vitamin D receptor and retinoid X receptor genes on metabolic traits

BMC Genomic Data

Table 1 Interaction analysis between vitamin D receptor ( VDR ) and retinoid X receptor-gamma ( RXRG ) polymorphisms in the discovery cohort (1958 British Birth Cohort) using linear regression

Outcome	VDR	RXRG	N in analysis	Interaction	Unadjusted P (adjusted P*) from joint LRT
	SNP	SNP		Beta ± SE
Low density lipoprotein cholesterol	rs3847987	rs283695	4,700	−0.12 ± 0.04	1.0x10⁻⁵ (0.03)
Low density lipoprotein cholesterol	rs11574143	rs283695	4,696	−0.13 ± 0.04	2.9x10⁻⁵ (0.04)
Serum triglycerides	rs11574143	rs17429123	4,843	0.13 ± 0.04	4.5x10⁻⁵ (0.01)
	rs11574143	rs10918172	4,873	0.13 ± 0.04	5.7x10⁻⁵ (0.02)
	rs3847987	rs17429123	4,849	0.12 ± 0.03	7.1x10⁻⁵ (0.02)
	rs3847987	rs10918172	4,880	0.12 ± 0.03	7.5x10⁻⁵ (0.05)
Waist Hip Ratio	rs2283342	rs157872	5,067	−0.01 ± 0.002	7.7x10⁻⁵ (0.04)

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