Arg12Trp
|
Mus musculus, Mus spretus[15, 18]
|
2D: tendency to random coil
|
|
3D: clash of side chain
|
Ser56Pro
|
Rattus norvegicus[14]
|
2D: tendency to random coil
|
|
3D: clash of side chain, less hydrogen bonds
|
Trp59Arg
|
Rattus spec.[15, 19]
|
2D: tendency to random coil
|
|
3D: change of side chain for ligand
|
Arg61Leu
|
Mus musculus, Mus spretus[15, 18]
|
2D: tendency to beta strand
|
|
3D: no important differences
|
Phe63Cys
|
Rattus spec.[15, 19]
|
2D: tendency to beta strand
|
|
3D: clash of side chain
|
Glu67Lys
|
Rattus spec.[15, 19]
|
2D, 3D: no important differences
|
|
Leu120Gln
|
Rattus norvegicus[14]
|
2D: conversion of helix to beta strand
|
|
3D: missing side chain for ligand binding
|
Leu128Gln
|
Rattus spec.[14, 15, 19]
|
2D: partial conversion of helix to beta strand
|
|
3D: no differences, interaction with ligand?
|
Leu128Ser
|
Mus musculus[14, 15]
|
2D: partial conversion of helix to beta strand
|
|
3D: no differences, interaction with ligand?
|
Tyr139Cys
|
Rattus spec., Mus musculus[14, 15, 19]
|
2D: tendency to beta strand
|
|
3D: no differences, interaction with ligand?
|
Tyr139Phe
|
Rattus spec.[14, 15, 19]
|
2D, 3D: no differences, interaction with ligand?
|
|
Tyr139Ser
|
Rattus spec.[14, 15, 19]
|
2D: tendency to random coil
|
|
3D: no differences, interaction with ligand?
|