Table 2 Genotype distributions, minor allele frequencies and unadjusted p-values for comparing genotype distribution according to diabetes status, additive allelic effects between diabetes groups
| Â | Non-diabetic | Diabetic | p-value | Overall |
|---|---|---|---|---|
N | 575 | 212 | Â | 787 |
IRS1 | Â | Â | Â | Â |
G/G, n (%) | 526 (91.5) | 199 (93.9) | 0.485 | 725 (92.1) |
G/A, n (%) | 48 (8.3) | 13 (6.1) | Â | 61 (7.7) |
A/A, n (%) | 1 (0.2) | 0 (0) | Â | 1 (0.1)) |
A, n (%) | 50 (4.4) | 13 (3.1) | 0.131 | 63 (4.0) |
HWE (p-value) | >0.999 | >0.999 | Â | >0.999 |
PPARG | Â | Â | Â | Â |
C/C, n (%) | 521 (90.6) | 183 (86.3) | 0.161 | 704 (89.4) |
C/G, n (%) | 53 (9.2) | 29 (13.7) | Â | 82 (10.4) |
G/G, n (%) | 1 (0.2) | 0 (0) | Â | 1 (0.1) |
G, n (%) | 55 (4.9) | 29 (6.8) | 0.012 | 84 (5.3) |
HWE (p-value) | >0.999 | 0.605 | Â | 0.719 |