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Table 7 Additive 1 estimates of SNPs within genes that have breed-dependent association 2 with feed efficiency

From: Single nucleotide polymorphisms and haplotypes associated with feed efficiency in beef cattle

Indicator SNP BTA Allele Gene symbol Gene name Breed3 P-Value
       AN 3/4 AN AN/SM 3/4 SM  
RFI rs110425294 5 A/G* AVIL Advillin −0.09 ± 0.06 0.09 ± 0.06 0.13 ± 0.05 −0.23 ± 0.08 5.71E-05
  rs42456314 12 A/G* GPC5 Glypican 5 −0.08 ± 0.07 −0.27 ± 0.07 −0.20 ± 0.06 −0.57 ± 0.08 2.69E-05
  rs29024448 17 G/T* RFC5 Replication factor C (activator 1) 5, 36.5 kDa 0.14 ± 0.06 0.31 ± 0.06 0.05 ± 0.05 0.20 ± 0.07 8.32E-06
  rs108942504 22 A/G* TMEM40 Transmembrane protein 40 0.05 ± 0.13 0.15 ± 0.12 0.17 ± 0.10 0.53 ± 0.13 3.07E-06
RADG rs109808044 3 A*/G SNED1 Sushi, nidogen and EGF-like domains 1 −0.04 ± 0.01 −0.08 ± 0.01 −0.01 ± 0.01 −0.03 ± 0.01 2.44E-05
  rs110742206 3 C/T* CSMD2 CUB and Sushi multiple domains 2 0.11 ± 0.03 0.11 ± 0.03 0.08 ± 0.02 0.23 ± 0.04 1.98E-05
  rs110690110 5 C*/G ERC1 ELKS/RAB6-interacting/CAST family member 1 −0.03 ± 0.01 −0.05 ± 0.01 −0.02 ± 0.01 −0.07 ± 0.01 2.49E-05
  rs110280556 6 A*/G UNC5C Unc-5 homolog C (C. elegans) −0.02 ± 0.01 −0.03 ± 0.01 0.00 ± 0.01 0.05 ± 0.01 6.65E-06
  rs41583989 24 C*/T DTNA Dystrobrevin, alpha −0.07 ± 0.02 0.04 ± 0.02 −0.02 ± 0.01 −0.04 ± 0.02 9.20E-05
RIG rs110131536 2 A*/G IGFBP5 Insulin-like growth factor binding protein 5 0.33 ± 0.14 0.40 ± 0.13 0.47 ± 0.12 −0.69 ± 0.20 2.30E-05
  rs110280556 6 A*/G UNC5C Unc-5 homolog C (C. elegans) −0.13 ± 0.08 −0.11 ± 0.08 0.06 ± 0.06 0.62 ± 0.11 3.88E-05
  rs41625438 12 C/T* DACH1 Dachshund homolog 1 (Drosophila) 0.06 ± 0.15 0.03 ± 0.15 0.05 ± 0.13 1.08 ± 0.21 8.82E-05
  rs42456314 12 A/G* GPC5 Glypican 5 0.22 ± 0.10 0.41 ± 0.10 0.36 ± 0.08 0.90 ± 0.12 2.35E-06
  rs41623603 16 A*/C CNST Consortin, connexin sorting protein 0.08 ± 0.10 0.10 ± 0.11 0.19 ± 0.09 −0.36 ± 0.13 5.13E-05
  rs29024448 17 G*/T RFC5 Replication factor C (activator 1) 5, 36.5 kDa −0.15 ± 0.09 −0.48 ± 0.09 −0.09 ± 0.07 −0.32 ± 0.11 1.71E-05
EI rs109053103 5 A*/G BIN2 Bridging integrator 2-like 0.28 ± 0.08 0.28 ± 0.08 −0.01 ± 0.06 0.36 ± 0.10 8.57E-05
  rs42456314 12 A/G* GPC5 Glypican 5 −0.10 ± 0.07 −0.26 ± 0.07 −0.21 ± 0.06 −0.55 ± 0.08 3.13E-05
  rs29024448 17 G*/T RFC5 Replication factor C (activator 1) 5, 36.5 kDa 0.11 ± 0.06 0.30 ± 0.06 0.07 ± 0.05 0.19 ± 0.07 3.23E-05
  rs108942504 22 A/G* TMEM40 Transmembrane protein 40 0.05 ± 0.12 0.09 ± 0.11 0.16 ± 0.10 0.48 ± 0.13 8.72E-06
  rs110206384 X A/G* F8 Coagulation factor VIII, procoagulant component 0.17 ± 0.05 −0.07 ± 0.05 −0.02 ± 0.04 0.01 ± 0.07 5.48E-05
EG rs110742206 3 C/T* CSMD2 CUB and Sushi multiple domains 2 0.54 ± 0.13 0.46 ± 0.12 0.35 ± 0.11 1.08 ± 0.17 7.31E-05
  rs42250803 17 A*/G SLC7A11 Solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.06 ± 0.06 −0.06 ± 0.05 0.02 ± 0.04 −0.31 ± 0.06 2.23E-05
  1. 1Contrast of the additive estimate between each level of breed and breed SM, relative to the minor allele.
  2. 2P-value < 0.0001.
  3. 3Estimate ± standard error.
  4. *Minor allele.