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Table 12 Enriched 1 functional annotation clusters and most enriched Gene Ontology and KEGG categories by SNP association

From: Single nucleotide polymorphisms and haplotypes associated with feed efficiency in beef cattle

SNP association

Cluster score

Category

Name

Number of genes

P-value

General

11.39

Molecular Function FAT

nucleotide binding

54

1.4E-19

 

3.6

Biological Process FAT

protein amino acid phosphorylation

16

3.4E-05

  

KEGG Pathway

MAPK signaling pathway

11

2.1E-04

  

Molecular Function FAT

protein serine/threonine kinase activity

12

4.1E-04

 

3.02

Molecular Function FAT

substrate specific channel activity

18

4.0E-09

  

Biological Process FAT

ion transport

17

6.5E-06

Breed-dependent

16.11

Molecular Function FAT

nucleotide binding

76

3.5E-26

  

Biological Process FAT

protein amino acid phosphorylation

27

7.8E-11

 

9.83

Biological Process FAT

phosphorus metabolic process

35

7.2E-13

  

Molecular Function FAT

protein kinase activity

25

2.3E-09

 

5.42

Biological Process FAT

ion transport

32

2.3E-13

  

Molecular Function FAT

ion channel activity

21

5.4E-10

 

4.35

Biological Process FAT

membrane invagination

9

7.4E-06

Diet-dependent

16.71

Molecular Function FAT

nucleotide binding

65

2.1E-26

  

Biological Process FAT

phosphorus metabolic process

33

5.0E-15

 

3.23

Molecular Function FAT

metallopeptidase activity

12

1.5E-07

  

Biological Process FAT

proteolysis

14

7.0E-03

  1. 1Cluster enrichment score > 3. The most significant Gene Ontology molecular function, biological process and KEGG pathway categories within each cluster are listed.