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Table 12 Enriched 1 functional annotation clusters and most enriched Gene Ontology and KEGG categories by SNP association

From: Single nucleotide polymorphisms and haplotypes associated with feed efficiency in beef cattle

SNP association Cluster score Category Name Number of genes P-value
General 11.39 Molecular Function FAT nucleotide binding 54 1.4E-19
  3.6 Biological Process FAT protein amino acid phosphorylation 16 3.4E-05
   KEGG Pathway MAPK signaling pathway 11 2.1E-04
   Molecular Function FAT protein serine/threonine kinase activity 12 4.1E-04
  3.02 Molecular Function FAT substrate specific channel activity 18 4.0E-09
   Biological Process FAT ion transport 17 6.5E-06
Breed-dependent 16.11 Molecular Function FAT nucleotide binding 76 3.5E-26
   Biological Process FAT protein amino acid phosphorylation 27 7.8E-11
  9.83 Biological Process FAT phosphorus metabolic process 35 7.2E-13
   Molecular Function FAT protein kinase activity 25 2.3E-09
  5.42 Biological Process FAT ion transport 32 2.3E-13
   Molecular Function FAT ion channel activity 21 5.4E-10
  4.35 Biological Process FAT membrane invagination 9 7.4E-06
Diet-dependent 16.71 Molecular Function FAT nucleotide binding 65 2.1E-26
   Biological Process FAT phosphorus metabolic process 33 5.0E-15
  3.23 Molecular Function FAT metallopeptidase activity 12 1.5E-07
   Biological Process FAT proteolysis 14 7.0E-03
  1. 1Cluster enrichment score > 3. The most significant Gene Ontology molecular function, biological process and KEGG pathway categories within each cluster are listed.